From Chapter 3:
Deacon, as the title of his book just quoted shows, was very fond of alliteration, and one sentence of his diatribe may be quoted. He warned his readers that tobacco-smoke was "very pernicious unto their bodies, too profluvious for many of their purses, and most pestiferous to the publike State." Much may be forgiven, however, to the introducer of so charming a term of abuse as "profluvious." Deacon's book takes the form of a dialogue, and after nearly 200 pages of argument, in which the unfortunate herb gets no mercy, one of the interlocutors, a trader in tobacco, is so convinced of the iniquity of his trade, and of his own parlous state if he continue therein, that he declares that the two hundred pounds' worth of this "beastly tobacco" which he owns, shall "presently packe to the fire," or else be sent "swimming down the Thames."

From Chapter 8:
The allusion in these verses to a "satiric wipe" refers to a passage in the poem entitled "Conversation," which Cowper had written in the previous year, 1781. In this passage tobacco is abused in terms which Cowper clearly felt to need modification after his personal intercourse with such a smoker as his friend Bull. In describing, in "Conversation," the manner in which a story is sometimes told, the poet says:

The pipe, with solemn interposing puff,
Makes half a sentence at a time enough;
The dozing sages drop the drowsy strain,
Then pause and puff—and speak, and pause again.
Such often, like the tube they so admire,
Important triflers! have more smoke than fire.