From Chapter 2:
But the apothecaries were the most usual salesmen, and their shops and the ordinaries were the customary day meeting-places for the more fashionable smokers. The taverns and inns, however, were also filled with smoke, and taverns were frequented by men of all social grades. Dekker speaks of the gallant leaving the tavern at night when "the spirit of wine and tobacco walkes" in his train. On the occasion of the accession of James I, 1603, when London was given up to rejoicing and revelry, we are told that "tobacconists [i.e. smokers] filled up whole Tavernes."

From Chapter 5:
When excavations were in progress early in 1901, preparatory to the construction of Kingsway and Aldwych, they included the removal of bodies from the burying-grounds of St. Clement Danes and St. Mary-le-Strand; and among the bones were found a couple of the curious tobacco-pipes called "plague-pipes," because they are supposed to have been used as a protection against infection by those whose office it was to bury the dead. These pipes have been dug up from time to time in numbers so large that one antiquary, Mr. H. Syer Cuming, has ventured to infer that "almost every person who ventured from home invoked the protection of tobacco."